Treatment Of Vitamin D Deficiency In Cystic Fibrosis
The optimal treatment for correcting or preventing vitamin d insufficiency in cystic fibrosis cf patients has not been established.
Treatment of vitamin d deficiency in cystic fibrosis. Treatment of vitamin d insufficiency in patients with cystic fibrosis requires high dose cholecalciferol or ergocalciferol. Randomized double blind placebo controlled large scale clinical trials are underway to evaluate the role. Vitamin d deficiency is a common finding in individuals with cystic fibrosis cf despite routine supplementation. Cholecalciferol d3 ergocalciferol d2 and uv light in raising or maintaining 25 oh d levels above 30 ng ml.
The objective was to develop evidence based clinical care guidelines for the screening diagnosis management and treatment of vitamin d deficiency in individuals with cystic fibrosis cf. Vitamin d deficiency occurs frequently in patients with cystic fibrosis cf. Vitamin d is important for optimal mineralization of bone and may be important for other comorbidities commonly occurring in patients with cf. Vitamin d status is important for bone health lung and immune function in patients with cystic fibrosis.
The aim of the study was to assess the relative efficacy of three modes of vitamin d therapy. The guidelines committee was comprised of physicians registered dietitians a pharmacist a nurse a parent of an individual with cf and a health scientist all with experience. Vitamin d deficiency in patients with cf can arise from various causes includin.