Dietary Protein Intake And Renal Function
Recent trends in weight loss diets have led to a substantial increase in protein intake by individuals.
Dietary protein intake and renal function. Dietary protein intake and renal function. The design of. Many studies suggest that limiting the amount of protein and including more plant based foods in the diet may help slow the loss of kidney function. Authors william f martin 1 lawrence e armstrong 2 nancy r rodriguez 1 affiliations 1 department of nutritional sciences university of.
Arch intern med 1989 149 211 212. High protein intake may lead to increased intraglomerular pressure and glomerular hyperfiltration. The nurses health study the prevention of renal and vascular end stage disease prevend study and the gubbio study 11 13. Epidemiologic studies on dietary protein and kidney function three epidemiologic studies reported longitudinal data on the association of protein intake with changes in kidney function over time.
These results suggest that in contrast with the important therapeutic effect of low protein intake on the progressive deterioration of kidney function in diseased kidneys such a diet does not significantly affect kidney function with normal aging in healthy subjects. Hence a low protein diet lpd of 0 6 0 8 g kg day is often recommended for the management of ckd. As a result the safety of habitually consuming dietary protein in excess of recommended intakes has been questioned. Among the notable points from this study was the findings of the european food safety authority efsa.
The modification of diet in renal disease intervention study suggested that dietary protein restriction may slow down kidney function decline in patients with an egfr between 25 and 55 ml min 1 73 m 2. Increase protein on the other hand once a person has started dialysis a higher amount of protein in the diet is necessary to help maintain blood protein levels and improve health. Dietary protein intake and renal function nutr metab lond. This can cause damage to glomerular structure leading to or aggravating chronic kidney disease ckd.
From a preventive perspective it is of interest to know whether protein restriction in patients with normal or mildly impaired kidney function. Dietary protein intake can modulate renal function and its role in renal disease has spawned an ongoing debate in the literature at the center of the controversy is the concern that habitual consumption of dietary protein in excess of recommended amounts promotes chronic renal disease through increased glomerular pressure and hyperfiltration 2 3. Guidelines for the nutrition management of adult chronic kidney disease consider the estimated nutrition needs of a renal patient in addition to presence of protein catabolism nutrient loss and widely ranging disease severity 1 specifically the renal diet aims to regulate intake of calories protein phosphate potassium sodium and fluid to promote optimal renal function and maintenance.