Dietary Protein And Kidney Function

This idea is based on a number of experimental and clinical observations as proved by the fact that the words dietary protein and kidney function generates in pubmed a list of approximately 9000 publications from 1927 to.

Dietary protein and kidney function. Chronic kidney disease ckd has a prevalence of approximately 13 and is most frequently caused by diabetes and hypertension. There is a consensus about the idea that dietary protein intake is a major physiological modulator of kidney function 2 3. The modification of diet in renal disease intervention study suggested that dietary protein restriction may slow down kidney function decline in patients with an egfr between 25 and 55 ml min 1 73 m 2. Found in overweight subjects that a reduction in protein intake from 91 to 70 g d decreased kidney volume by 6 2 cm 3 and gfr by 7 1 ml min whereas an increase in protein from 91 to 108 g d increased kidney volume by 9 1 cm 3 and gfr by 5 2 ml min without any change in microalbuminuria.

An association of baseline protein intake with long term kidney function decline was absent in the general population and or persons with normal kidney function but was significantly positive in persons with below normal kidney function. From a preventive perspective it is of interest to know whether protein restriction in patients with normal or mildly impaired kidney function. In population studies ckd etiology is often uncertain.