Dietary Sodium And Urinary Calcium

Both hypo and hypercalciuria are associated with adverse skeletal effects that may have important therapeutic implications.

Dietary sodium and urinary calcium. The average amount of daily sodium and calcium intake were 3 466 mg and 813 mg respectively. Average dietary sodium intake and 24 hour urinary sodium excretion showed significant positive linear correlation r 0 29 p 0 006. High urinary calcium hypercalciuria may be due to excess dietary sodium intake 3g day increased intestinal absorption of calcium defective renal tubular absorption of calcium high bone resorption or idiopathic 143. During this same period the urinary ça24 excretion in shr was enhanced significantly p 0 01 and the urinary calcium sodium ratio was elevated during the high sodium intake period.

Calcium excretion also correlated positively with daily urinary excretion of urea. The correlation between urinary sodium and calcium is generally sodium driven i e it is the sodium load that influences urinary calcium rather than vice versa but the converse may also occur as after an oral calcium load or in hypercalcemia. Urinary sodium and calcium excretion values over 24 h were positively correlated for males r 0 44 p less than 0 05 and females r 0 80 p less than 0 001. The relationship between dietary sodium intake and urinary calcium excretion was also examined in 12 healthy young adults under controlled dietary conditions.

Calcium channel antagonists including the 1 4 dihydropyridines nifedipine and nitrendipine are effective in reducing high blood pressure in hypertensive. Barr higher urinary sodium a proxy for intake is associated with increased calcium excretion and lower hip bone density in healthy young women with lower calcium intakes nutrients 10 3390 nu3110951 3 11 951 961 2011.