Effect Of Dietary Omega 3 Fatty Acids On Coronary Atherosclerosis

Two hundred twenty three patients hospitalized for diagnostic coronary angiography at the university of munich between 1992 and 1994 were randomized to receive fish oil capsules or a placebo.

Effect of dietary omega 3 fatty acids on coronary atherosclerosis. Effect of dietary supplementation with omega 3 fatty acids on progression of atherosclerosis in carotid arteries. Hjerkinn em 1 abdelnoor m breivik l bergengen l ellingsen i seljeflot i aase o ole klemsdal t hjermann i arnesen h. Effect of diet or very long chain omega 3 fatty acids on progression of atherosclerosis evaluated by carotid plaques intima media thickness and by pulse wave propagation in elderly men with hypercholesterolaemia. Omega 3 polyunsaturated fatty acids ω 3 pufa from fish oil slow atherosclerosis progression in coronary arteries as we showed in a randomized double blind placebo controlled clinical trial.

The results of experimental observational and randomized studies do not consistently support the use of omega 3 fa docosahexaenoic acid dha and eicosapentaenoic acid epa for cardiovascular event prevention. The effect can be ascribed to anti inflammatory vasodilating antiarrhythmic antihypertensive activities and lowering of triacyl glycerol level. To determine the effect of dietary intake of omega 3 fatty acids on the course of coronary artery atherosclerosis in humans. In addition to this reduction in atherosclerotic lesion size morphological characteristics of more stable lesions have also been observed 14.

Angerer p kothny w störk s von schacky c. Few trials in humans have examined this potential. Despite somewhat variable results the main conclusion which emerges from the majority of the studies is a beneficial effect of dietary omega 3 fatty acids on murine atherosclerosis. Embedded in this trial the present study examined the influence of 2 years of dietary supplementation with 1 65 g ω 3 pufa per day on progression of carotid atherosclerosis in 223.

Omega 3 fatty acids fa have shown beneficial effects on coronary heart disease chd but data are contradictory. Cardiovasc res 54 1 183 190 01 apr 2002 cited by 45 articles pmid. To determine the effect of dietary intake of omega 3 fatty acids on the course of coronary artery atherosclerosis in humans. Embedded in this trial the present study examined the influence of 2 years of dietary supplementation with 1 65 g omega 3 pufa per day on progression of carotid atherosclerosis in 223.

Omega 3 polyunsaturated fatty acids omega 3 pufa from fish oil slow atherosclerosis progression in coronary arteries as we showed in a randomized double blind placebo controlled clinical trial. The effect of fish oil on atherosclerosis overall appears to be small or inconsistent when compared to the degree to which they prevent cardiovascular events.