Dietary Nitrate Supplementation And Blood Pressure

Recent studies have shown that dietary nitrate supplementation can reduce blood pressure and improve endothelial dysfunction.

Dietary nitrate supplementation and blood pressure. 23 plasma nitrite concentration was elevated by 2 7 fold from baseline. Dietary nitrate supplementation providing 6 mmol nitrate daily for 4 weeks caused substantial increases in plasma nitrate concentrations 5 5 fold and is similar to the peak fold increases in previous studies with similar doses. A systematic review and meta analysis. The reduced fold increase.

Blood pressure cardiovascular function and uteroplacental blood flow was assessed at baseline and following acute 3 h and prolonged 8 days supplementation. An inverse relationship was seen between dose of nitrate consumed and corresponding systolic blood pressure reduction with doses of nitrate as low as 3 mmol of nitrate reducing systolic blood pressure by 3 mmhg. Plasma and salivary samples were collected for analysis of nitrate and nitrite concentrations and acceptability of this dietary intervention was assessed based on questionnaire feedback. Proposed mechanisms involve the generation of nitrite and subsequently nitric oxide which promotes vasodilation to lower blood pressure 9.