Dietary Iron Intake Cardiovascular Disease

High dietary haem iron intake was associated with a 65 increase in chd risk hazard ratio hr 1 65.

Dietary iron intake cardiovascular disease. Dietary intake of heme iron mainly from red meat also was not significantly associated with risk of coronary heart disease. 1 07 2 53 after adjustment for cardiovascular and nutritional risk factors. In addition two studies reported that dietary iron intake may serve as a protective factor against the development of hypertension and mi. In a random fifth of these people dietary iron intake was assessed by a dietary history.

However incidence of fatal coronary disease or nonfatal myocardial infarction was higher among men in the top quintile of heme iron intake compared with men in the lowest quintile rr 1 42. To the best of our knowledge this is the first dose response meta analysis to examine the effect of dietary iron intake on total cardiovascular disease morbidity and mortality. This risk was not modified by additional risk factors menstruation or antioxidant intake. Higher dietary intake of heme iron is associated with an increased risk of cardiovascular disease whereas no association was found between cvd and non heme iron intake or total iron intake.

P for trend 0 009 for total stroke and 1 27 1 01 1 58. Therefore the hazardous effect of high dietary iron intake and the protective effect of menstruation on body iron stores and thereby cardiovascular disease risk could not. Higher dietary intake of heme iron is associated with an increased risk of cardiovascular disease whereas no association was found between cvd and non heme iron intake or total iron intake. The multivariable hazard ratio for the highest versus the lowest quintile of total iron intake was 1 43 95 ci 1 02 2 00.

Dietary intake of total iron was positively associated with mortality from total and ischemic stroke and total cvd in men. 0 023 for total cvd in men. Many studies have investigated the association between dietary iron intake and death due to cardiovascular disease cvd but the results were inconsistent. We performed a dose response meta analysis to quantitatively assess the risk of cvd mortality with dietary intake of iron total iron heme iron and non heme iron.

Most previous studies that have investigated the association between dietary iron intake and cardiovascular disease risk were conducted in populations of both men and women. The study was observational without any interventions. These findings may have important public health implications with respect to preventing cardiovascular diseas. We aimed to quantitatively summarize the literature on the association between dietary iron intake body iron stores and chd risk by conducting a meta analysis of prospective.

Mortality from coronary heart disease. 95 confidence interval ci. These findings may have important public health implications with respect to preventing cardiovascular disease.