Dietary Inorganic Nitrate In Cardiovascular Health

Evidence related to the treatment of hypertension through sources of inorganic nitrate has been presented.

Dietary inorganic nitrate in cardiovascular health. Dietary nitrate supplementation in cardiovascular health. The national heart lung and blood institute convened this workshop to discuss the results of recent research on the effects of inorganic nitrate and nitrite on the cardiovascular system possible long term effects of these compounds in the diet and drinking water and future research needs including population wide effects examined through epidemiological studies. Emerging evidence strongly suggests that dietary nitrate derived in the diet primarily from vegetables could contribute to cardiovascular health via effects on nitric oxide no status. Dietary inorganic nitrate and nitrite have for half a century been considered toxic constituents in our diet because of their proposed role in the development of gastric cancer and other malignancies.

1 2 for this reason the levels of these anions are strictly regulated in our food and drinking water. Hazard ratio of inorganic nitrate and its active metabolite nitrite remains less clear and must be studied in prospective controlled studies. Approximately 60 80 inorganic nitrate exposure in the human diet is contributed by vegetable consumption. For example the dietary approaches to stop hypertension dash dietary pattern 10 192 which emphasizes fruits vegetables and low fat dairy foods and includes whole grains poultry fish and nuts can.

Apart from the dietary aspects of nitrate and nitrate the interest in. Dietary inorganic nitrate has had a notoriously bad reputation for more than 50 years mainly because of its proposed association with formation of nitrosamines and development of cancer tannenbaum and correa 1985 tricker and preussmann 1991 this has led to strict regulations regarding the allowable levels of nitrate in our food and drinking water. Dietary inorganic nitrate especially derived from vegetables serves as a substrate for endogenous nitric oxide no which has been confirmed to possess functions of regulating cardiovascular. An ergogenic aid or exercise therapeutic.

At this point in time however the benefit. Although inorganic nitrate is a relatively stable molecule under specific conditions it can be metabolised in the body to produce no via the newly discovered nitrate nitrite no pathway. This review is the first of its kind to outline the current evidence for inorganic nitrate supplementation as a therapeutic intervention to restore exercise tolerance and improve quality of life in patients with cardiovascular diseases. Pressure and reducing cardiovascular disease risks.