Dietary Fat And Cancer

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Dietary fat and cancer. Dietary fat and cancer. In the early 1980s most nutrition experts believed that dietary fat was a major cause of breast cancer. Like breast cancer there is a long history of literature regarding dietary fat and crc risk stemming from international correlation studies armstrong doll 1975. 1 division of public health sciences fred hutchinson cancer research center seattle wa 98104.

We prospectively evaluated fat intake as predictor of developing breast cancer bc subtypes defined by estrogen receptor er progesterone receptor pr and human epidermal growth factor 2 receptor her2 in a large n 337327 heterogeneous cohort of women with 10062 bc case patients after 11 5 years estimating bc hazard ratios hrs by cox proportional hazard modeling. 2002 dec 30 113 suppl 9b 63s 70s. The role of dietary fat in other cancers is not as clearly defined although it appears that associations of fat intake with colorectal cancer is specific to fat from animal sources or may be attributed to meat intake rather than fat per se 6 the association of dietary fat with prostate cancer is also unclear although epidemiologic and other. With regard to dietary fat the western diet is characterised by an increased energy intake and decreased energy expenditure increased sfa n 6 fatty acid fa and trans fa with.

Henderson mm kushi lh thompson dj gorbach sl clifford ck insull w jr moskowitz m thompson rs. Feasibility of a randomized trial of a low fat diet for the prevention of breast cancer. Affiliation 1 division of research kaiser permanente oakland california 94612 usa. As this cancer currents post explains researchers also showed that an anti obesity drug that targets a protein that controls fat synthesis could potentially be used to treat metastatic prostate cance.

Dietary fat and cancer am j med. A new study in mice has revealed a molecular link between a high fat diet and the growth and spread of prostate cancer. Prentice rl 1 sheppard l. Many recognised health problems are associated with excessive intake of dietary fat such as obesity insulin resistance chd and certain types of cancer 4 6.

However in adults the percentage of calories consumed from total fat appears to have no significant association with cancer risk and there is currently no clear evidence linking any specific type of fat with cancer incidence. These studies showed a large regional variation in crc incidence. Dietary compliance in the women s health trial vanguard study.